George Panagis,PhD



School of Social Sciences / Department of Psychology

University of Crete

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Tel: +30 28310 77544

Lab web page:


1988-92        BS in Philosophy and Social Sciences

1992-95        BS in Psychology

1992-96        PhD in Neuropsychopharmacology

1997-98        Postdoctoral Fellow


Research Interests

My research focuses on the pharmacological and neural mechanisms for reward, drug addiction, and psychiatric disorders. In the Behavioral Neuroscience Laboratory, we also conduct basic research in order to delineate the roles of predisposing and/or protective factors in the development of drug abuse and addiction. Experimental approaches include various behavioral methodologies, (intracranial self-stimulation, place preference, open field, elevated plus maze, forced swim test), intra-cerebral and systemic pharmacology). In collaboration with other researchers, we have conducted neurochemical, histochemical and morphologicalanalyses to determine cellular and molecular correlates for the behaviors that we study.



Ministry of Education, General Secretariat-Ministry of Research and Development,  Special Account for Research of the University of Crete  


Recent Publications or Selected Publications

Pitsilis, G., Spyridakos, D., Nomikos, G.G., & Panagis, G. (2017). Adolescent female cannabinoid exposure alters the reward-facilitating effects of Δ9-tetrahydrocannabinol and d-amphetamine in the adult male offspring. Frontiers in Neuropharmacology, Front. Pharmacol. 8:225.doi: 10.3389/fphar.2017.0022.

Mavrikaki, M., Kastellakis A., Schintu N., Nomikos, G.G., Svenningsson P., & Panagis, G. (2014). Effects of lithium and aripiprazole on brain stimulation reward and neuroplasticity markers in the limbic forebrain. European Neuropsychopharmacology, 24(4), 630-638.

Katsidoni, V., Kastellakis A., & Panagis, G. (2013). Biphasic effects of Δ9-tetrahydrocannabinol on brain stimulation reward and motor activity. International Journal of Neuropsychopharmacology, 16, 2273-2284.

Katsidoni, V., Anagnostou, I., & Panagis, G. (2013).  Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT1A receptors in the dorsal raphe nucleus, Addiction Biology, 18, 286-296.

Katsidoni, V., Apazoglou, K., & Panagis, G. (2011). Role of serotonin 5-HT2A and 5-HT2C receptors on brain stimulation reward and the reward-facilitating effect of cocaine. Psychopharmacology, 213, 337-354.